Hyaluronic Acid gel is mainly used in medical and cosmetic areas, and now has a lot of substitutes for collagen, placenta and Botox. Statistics show that 2004, Global hyaluronic Acid Gel application of the relevant market scale of about 3 billion U.S. dollars, cosmetic products and products for the treatment of skin care product market accounted for half. Europe, the United States and Japan are the largest markets for the production and use of hyaluronic acid gel products and are expected to continue to grow by 15% per cent a year in the future. There are two kinds of microbial fermentation methods in the production of hyaluronic acid gel by tissue extraction. Now there are only 5 international companies in the world with microbial fermentation process to produce medical grade hyaluronic Acid gel technology. In the second half of the 2004, the demand for hyaluronic acid gels surged in the European and American markets, resulting in shortages of raw materials and rising prices. Domestic authorities have predicted that the demand for Hyaluronic acid gels will continue beyond 2006.
Hyaluronic Acid gel: Hyaluronic Acid gel, the name of hyaluronic acid (hyaluronic acid, referred to as ha) or the disaccharide, consisting of a unit (grape acid-n-glucosamine), a straight-chain macromolecule polysaccharide, is a natural substance in the organization. In nature, widely existed in vertebrate connective tissue, mucous tissue, eyeball lens and some bacteria in the film, in the dermis layer of human skin plays an important role in the matrix, whether it is the overall maintenance of the structure or the transport between cells have a very important function.
Hyaluronic acid (HA) is a kind of acidic polysaccharide-like macromolecule substance which is widely existed in human and animal connective tissue, and it shows its application value in tissue engineering because of its various physiological functions and the cell aggregation in the process of regulating tissue formation.