Hyaluronic Acid gel is mainly used in medical and cosmetic areas, and now has a significant replacement for collagen. The potential of placenta and Clostridium botulinum. Statistics show that 2004, Global hyaluronic Acid Gel application of the relevant market scale of about 3 billion U.S. dollars, cosmetic products and products for the treatment of skin care product market accounted for half. Europe, the United States and Japan are the largest markets for the production and use of hyaluronic acid gel products and are expected to continue to grow by 15% per cent a year in the future.
There are two kinds of microbial fermentation methods in the production of hyaluronic acid gel by tissue extraction. Now there are only 5 international companies in the world with microbial fermentation process to produce medical grade hyaluronic Acid gel technology. In the second half of the 2004, the demand for hyaluronic acid gels surged in the European and American markets, resulting in shortages of raw materials and rising prices. Domestic authorities predict that the supply of oral hyaluronic acid gels will continue beyond 2006.