1934 A.D. Meyer, an ophthalmology professor at Columbia University, first separated the hyaluronic acid gel from the vitreous of bovine eyes and analyzed its structure. Because it is extracted from hyaloid (vitreous, Greek), the uronic acid (glycolysis) is named hyaluronic acid (Hyaluronic acid gel). The structure of hyaluronic acid gels is mainly composed of two sugars (disaccharide), ethyl mercaptan (n-acetyl-d-glucosamine) and Glucan (D-glucuronic AICD), weight between 105-107dalton.
Hyaluronic Acid gel can be said to be the skin moisturizing factor, he has the ability to absorb 500-1000 times volume, compared to collagen molecules can only carry 30 times times the water, can be said to be the most powerful moisturizing material in the literature today. In addition to the moisture after the expansion of the volume of characteristics, coupled with bio-stability, difficult to transfer and water, also makes oral hyaluronic acid gel as a good choice for tissue filler. The hyaluronic acid gels in nature are quickly metabolized, therefore, in order to be a filler between the tissues, the polymer (polymer) must be made, and the bond between the molecules provides not only the permanence of the organism, but also the viscosity of the Hyaluronic acid Gel (viscosity) and the hydrophobicity (water insolubility).